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Enzyme:CYP2C19: Revision history

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22 May 2026

19 May 2026

  • curprev 22:3922:39, 19 May 2026 MDElliottMD talk contribs 17,387 bytes +5,291 Consolidate enzyme entity page to canonical Pharmacopedia: sandbox location per Mark 2026-05-19. Full retrofitted version: history-first spine, collapsible-sortable substrate table, comprehensive-tables pointer, all PMIDs NCBI-eutils-verified, zero em-dashes. For CYP2D6/CYP3A4/CYP2C19 this replaces the earlier pre-retrofit draft with the full version; for the other 8 enzymes this is the first save at the canonical location. Resolves a cross-session sandbox-location duplication: the User:MDEll...
  • curprev 16:4316:43, 19 May 2026 MDElliottMD talk contribs 12,096 bytes +12,096 Pharmacogenomics entity page: CYP2C19. Three CPIC Level A indications (clopidogrel + PPIs + SSRIs/voriconazole). Five-phenotype classification PM/IM/NM/RM/UM driven by *2 / *3 / *17 alleles; ancestry-frequency variation called out. Clopidogrel prodrug-activation story; PPI dose-by-phenotype; SSRI QT-prolongation in PMs. 9 inline cites across 4 PMID-verified refs: Wilkinson 2005 NEJM (PMID 15917386), Lee/Luzum 2022 CPIC clopidogrel (PMID 35034351), Lima 2021 CPIC PPI (PMID 32770672), Bousman 2...