Category:Drug-metabolizing enzymes: Revision history

22 May 2026

• curprev 16:5716:57, 22 May 2026 MDElliottMD talk contribs 8,676 bytes −633 Category:Drug-metabolizing enzymes: repoint the 11 enzyme links onto the Enzyme: namespace; correct the stale sandbox note (task #24)

19 May 2026

• curprev 23:1823:18, 19 May 2026 MDElliottMD talk contribs 9,309 bytes +33 Add Category:CuratedCategoryPage marker tag per interface-claude 2026-05-20. This marker lets MediaWiki:Common.css suppress MediaWiki's auto-generated 'Pages in category' list, which otherwise renders the member list a second time (machine-formatted) below the curated 'Enzymes indexed' section. Marker is the general non-MedCategory equivalent of the existing MedCategoryFull marker. No prose change.
• curprev 23:0123:01, 19 May 2026 MDElliottMD talk contribs 9,276 bytes +5,616 Rewrite category intro: replace the wiki-plumbing lead with a descriptive, history-first account of what a drug-metabolizing enzyme is. Covers the cytochrome P450 naming (Omura and Sato 1964, the 450 nm absorption peak, PMID 14209971), the phase-I / phase-II framework, the mixed-function-oxidase mechanism, the enzyme families, and the detoxification-versus-bioactivation duality (Pott 1775 chimney-sweep scrotal cancer as the historical thread; CYP1A/CYP3A4/CYP2E1 carcinogen activation as the m...
• curprev 22:3922:39, 19 May 2026 MDElliottMD talk contribs 3,660 bytes +3,660 Create Category:Drug-metabolizing enzymes: curated index of the 11 enzyme entity pages (8 CYPs + UGT1A1 + TPMT + NUDT15) at their canonical Pharmacopedia: sandbox location, grouped by enzyme family, with scope notes distinguishing enzymes from transporters and non-enzyme variant loci. Parent Category:Pharmacogenomics.