MDElliottMD: home-claude category backfill (parser-claude gap closure)

2026-05-23T10:43:43Z

home-claude category backfill (parser-claude gap closure)

← Older revision		Revision as of 10:43, 23 May 2026
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	== References ==		== References ==
	<references />		<references />
			[[Category:Vitamins]]
			[[Category:Water-soluble vitamins]]
			[[Category:Antioxidants]]

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #226

2026-05-23T04:19:16Z

parser-claude batch MedTemplate pre-fill, Top 300 #226

New page

{{MedTemplate
| generic = Ascorbic acid (vitamin C)
| brand = Generic; huge OTC presence
| structure =
| classes = [[:Category:Vitamins|Vitamin]], [[:Category:Water-soluble_vitamins|Water-soluble vitamin]], [[:Category:Antioxidants|Antioxidant]]
| uses = <vote slug="scurvy-use">Scurvy (vitamin C deficiency)</vote>, <vote slug="iron-deficiency-coadjuvant-use">Enhancement of nonheme iron absorption</vote>, <vote slug="urine-acidification-use">Urinary acidification (selected, e.g. methemoglobinemia treatment adjunct)</vote>, <vote slug="general-supplementation-use">General supplementation (limited evidence for prevention of common cold or other indications)</vote>
| starting_dose = General supplementation 75-90 mg/d (RDA); scurvy treatment 100-1000 mg/d for several weeks; megadose claims unsupported
| preparations = 100, 250, 500, 1000 mg tablets, chewables, gummies, effervescent; IV (specialty)
| fda_max = UL 2000 mg/d in adults
| pill_id =
| routes = Oral, IV
| onset = Days for symptom improvement in scurvy
| duration = Hours
| halflife = ~10-20 days (steady-state body pool); single dose plasma ~2 hours
| bioavailability = ~70-90% at typical doses; saturable at high doses (>500 mg)
| pregnancy = Safe at routine doses; routinely supplemented in pregnancy.{{citation needed}}
| legal = OTC in US
| mechanism = <vote slug="ascorbic-acid-mech-claim">Ascorbate is an essential cofactor for hydroxylase enzymes including prolyl and lysyl hydroxylases (collagen synthesis), dopamine β-hydroxylase, and the demethylating Fe(II)/α-ketoglutarate-dependent dioxygenases (including TET enzymes in DNA demethylation); it also serves as a major water-soluble antioxidant, recycling other antioxidants like tocopherol and glutathione.</vote> Deficiency (scurvy) presents with hemorrhagic gums, perifollicular hemorrhage, hair coiling, fatigue, and poor wound healing — direct consequences of impaired collagen cross-linking. Megadose claims for cold prevention and other indications are not supported by high-quality evidence beyond minor effects on cold duration in some studies. High-dose supplementation may raise risk of oxalate kidney stones in predisposed individuals.
}}

== References ==
<references />

Ascorbic Acid - Revision history

MDElliottMD: home-claude category backfill (parser-claude gap closure)

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #226