MDElliottMD: home-claude category backfill (parser-claude gap closure)

2026-05-23T10:43:30Z

home-claude category backfill (parser-claude gap closure)

← Older revision		Revision as of 10:43, 23 May 2026
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	== References ==		== References ==
	<references />		<references />
			[[Category:H1 receptor antagonists]]
			[[Category:Antihistamines]]

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #55

2026-05-23T03:34:51Z

parser-claude batch MedTemplate pre-fill, Top 300 #55

New page

{{MedTemplate
| generic = Cetirizine
| brand = Zyrtec, Zyrtec-D
| structure =
| classes = [[:Category:H1_receptor_antagonists|Histamine H1 receptor antagonist (second-generation)]], [[:Category:Antihistamines|Antihistamine]]
| uses = <vote slug="allergic-rhinitis-use">Allergic rhinitis</vote>, <vote slug="chronic-urticaria-use">Chronic idiopathic urticaria</vote>, <vote slug="allergic-conjunctivitis-use">Allergic conjunctivitis</vote>
| starting_dose = 10 mg PO once daily (5 mg in older adults or if sedation occurs)
| preparations = 5 mg, 10 mg tablets; 5 mg, 10 mg chewables; 1 mg/mL oral syrup; OTC
| fda_max = 10 mg/d (adults)
| pill_id =
| routes = Oral
| onset = 30-60 minutes
| duration = 24 hours
| halflife = 8-10 hours (longer in elderly and renal impairment)<ref name="zyrtec-label">FDA Prescribing Information, Zyrtec (cetirizine HCl), Johnson & Johnson Consumer, current revision. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019835s062lbl.pdf</ref>
| bioavailability = High (oral); not significantly affected by food<ref name="zyrtec-label" />
| pregnancy = Generally considered safe; widely used. Levocetirizine (the R-enantiomer) is an alternative with similar safety.{{citation needed}}
| legal = OTC in US
| mechanism = <vote slug="cetirizine-mech-claim">Cetirizine is a selective peripheral H1 receptor antagonist; as a carboxylated zwitterion at physiologic pH it crosses the blood-brain barrier far less than first-generation antihistamines, producing materially less sedation while retaining peripheral antihistaminic activity.</vote> Minimal CYP metabolism; mostly renally cleared unchanged. Cetirizine is the active racemate; levocetirizine is the active R-enantiomer marketed separately<ref name="zyrtec-label" />.
}}

== References ==
<references />

Cetirizine - Revision history

MDElliottMD: home-claude category backfill (parser-claude gap closure)

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #55