MDElliottMD: home-claude category backfill (parser-claude gap closure)

2026-05-23T10:43:43Z

home-claude category backfill (parser-claude gap closure)

← Older revision		Revision as of 10:43, 23 May 2026
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	== References ==		== References ==
	<references />		<references />
			[[Category:Antifungals]]
			[[Category:Topical antifungals]]
			[[Category:Hydroxypyridones]]

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #278

2026-05-23T04:15:08Z

parser-claude batch MedTemplate pre-fill, Top 300 #278

New page

{{MedTemplate
| generic = Ciclopirox
| brand = Penlac (nail lacquer), Loprox (cream/lotion/shampoo)
| structure =
| classes = [[:Category:Antifungals|Antifungal]], [[:Category:Topical_antifungals|Topical antifungal]], [[:Category:Hydroxypyridones|Hydroxypyridone]]
| uses = <vote slug="tinea-pedis-use">Tinea pedis / cruris / corporis</vote>, <vote slug="cutaneous-candidiasis-use">Cutaneous candidiasis</vote>, <vote slug="seborrheic-dermatitis-use">Seborrheic dermatitis (shampoo)</vote>, <vote slug="onychomycosis-mild-use">Onychomycosis (mild distal subungual; nail lacquer)</vote>
| starting_dose = Topical cream/lotion BID; shampoo twice weekly; nail lacquer (Penlac) once daily for up to 48 weeks
| preparations = 0.77% topical cream, lotion, suspension; 1% shampoo; 8% nail lacquer (Penlac)
| fda_max = BID topical; once daily nail lacquer
| pill_id =
| routes = Topical
| onset = Days for dermatophyte clearance; nail clearance over months
| duration = Hours per application
| halflife = Not meaningfully described (topical local action)<ref name="penlac-label">FDA Prescribing Information, Penlac (ciclopirox) topical solution, Sanofi-Aventis, current revision. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021022s015lbl.pdf</ref>
| bioavailability = Topical with minimal systemic absorption<ref name="penlac-label" />
| pregnancy = Generally considered safe (minimal systemic absorption).{{citation needed}}
| legal = [[USLegal:Prescription only|Rx-only]] in US
| mechanism = <vote slug="ciclopirox-mech-claim">Ciclopirox is a hydroxypyridone antifungal with a mechanism distinct from azoles and allylamines; it chelates polyvalent cations (Fe³⁺, Al³⁺), disrupting cofactor-dependent fungal enzymes (cytochromes, catalases, peroxidases) and producing fungicidal activity against dermatophytes, Candida, and Malassezia.</vote> Onychomycosis cure rates with nail lacquer are modest (mycologic cure ~30-50%, complete cure ~5-12% at 48 weeks); oral terbinafine remains substantially more effective when systemic therapy is acceptable<ref name="penlac-label" />.
}}

== References ==
<references />

Ciclopirox - Revision history

MDElliottMD: home-claude category backfill (parser-claude gap closure)

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #278