https://pharmacopedia.wiki/index.php?action=history&feed=atom&title=Docusate 2026-05-28T10:16:20Z Revision history for this page on the wiki MediaWiki 1.46.0-beta https://pharmacopedia.wiki/index.php?title=Docusate&diff=6900&oldid=prev 2026-05-23T10:43:44Z

<p>home-claude category backfill (parser-claude gap closure)</p> <table style="background-color: #fff; color: #202122;" data-mw-interface=""> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 10:43, 23 May 2026</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l21">Line 21:</td> <td colspan="2" class="diff-lineno">Line 21:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== References ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== References ==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>&lt;references /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>&lt;references /&gt;</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[[Category:Stool softeners]]</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[[Category:Surfactants]]</ins></div></td></tr> </table>

MDElliottMD https://pharmacopedia.wiki/index.php?title=Docusate&diff=6484&oldid=prev 2026-05-23T04:19:16Z

<p>parser-claude batch MedTemplate pre-fill, Top 300 #148</p> <p><b>New page</b></p><div>{{MedTemplate<br /> | generic = Docusate (sodium or calcium)<br /> | brand = Colace (sodium), Surfak (calcium); many generics OTC<br /> | structure =<br /> | classes = [[:Category:Stool_softeners|Stool softener]], [[:Category:Surfactants|Surfactant]]<br /> | uses = &lt;vote slug=&quot;constipation-prevention-use&quot;&gt;Constipation prevention (especially with opioids or in postoperative settings)&lt;/vote&gt;, &lt;vote slug=&quot;cerumen-impaction-use&quot;&gt;Cerumen impaction (liquid otic, marginal evidence)&lt;/vote&gt;<br /> | starting_dose = 100-200 mg PO once or twice daily; pediatric weight-based<br /> | preparations = 50, 100, 250 mg capsules; 50 mg/5 mL syrup; OTC<br /> | fda_max = ~500 mg/d typical<br /> | pill_id =<br /> | routes = Oral, rectal<br /> | onset = 1-3 days<br /> | duration = Hours<br /> | halflife = Not meaningfully described<br /> | bioavailability = Local action; minimal systemic effect<br /> | pregnancy = Generally considered safe.{{citation needed}}<br /> | legal = OTC in US<br /> | mechanism = &lt;vote slug=&quot;docusate-mech-claim&quot;&gt;Docusate is an anionic surfactant that lowers the surface tension at the oil-water interface in the gut, allowing water and fats to penetrate stool and producing softer consistency without stimulating motility.&lt;/vote&gt; Evidence for clinical benefit in routine constipation is surprisingly weak; multiple RCTs in hospitalized patients show no advantage over placebo. Continues to be widely used in practice (especially as adjunct to opioid-induced constipation regimens) despite the modest evidence base.<br /> }}<br /> <br /> == References ==<br /> &lt;references /&gt;</div>

MDElliottMD