MDElliottMD: home-claude category backfill (parser-claude gap closure)

2026-05-23T10:43:32Z

home-claude category backfill (parser-claude gap closure)

← Older revision		Revision as of 10:43, 23 May 2026
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	== References ==		== References ==
	<references />		<references />
			[[Category:Vitamins]]
			[[Category:B-vitamins]]
			[[Category:Hematinics]]

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #94

2026-05-23T03:46:15Z

parser-claude batch MedTemplate pre-fill, Top 300 #94

New page

{{MedTemplate
| generic = Folic acid (folate, pteroylglutamic acid)
| brand = Folvite; mostly generic
| structure =
| classes = [[:Category:Vitamins|Vitamin]], [[:Category:B-vitamins|B-vitamin]], [[:Category:Hematinics|Hematinic]]
| uses = <vote slug="folate-deficiency-anemia-use">Folate-deficiency megaloblastic anemia</vote>, <vote slug="neural-tube-defect-prevention-use">Neural tube defect prevention in pregnancy</vote>, <vote slug="methotrexate-rescue-use">Methotrexate-associated stomatitis/GI toxicity reduction</vote>, <vote slug="homocystinuria-use">Homocystinuria adjunct</vote>
| starting_dose = 0.4 mg PO daily (general prevention); 0.8-1 mg/d in pregnancy; 4 mg/d for women with prior NTD-affected pregnancy; 1 mg/d during methotrexate therapy
| preparations = 0.4, 0.8, 1 mg OTC; 1 mg Rx; 5 mg/mL injection
| fda_max = 1 mg/d typical Rx; higher in specific indications
| pill_id =
| routes = Oral, IM, IV, SC
| onset = Hematologic response within days
| duration = N/A (replacement)
| halflife = ~0.5 hours plasma; tissue retention longer
| bioavailability = High (oral)
| pregnancy = Routinely supplemented in pregnancy and preconception to prevent neural tube defects.{{citation needed}}
| legal = OTC (low-dose) and [[USLegal:Prescription only|Rx-only]] (1 mg, injectable) in US
| mechanism = <vote slug="folic-acid-mech-claim">Folic acid is the synthetic form of folate; following absorption it is reduced by dihydrofolate reductase to tetrahydrofolate (THF), the carrier of one-carbon units required for thymidylate, purine, and amino acid synthesis.</vote> The dramatic effect on neural tube defects (Medical Research Council Vitamin Study, 1991) led to US mandatory cereal-grain fortification (1998) and population-level NTD reduction. In folate-deficient megaloblastic anemia presenting with neurologic symptoms, B12 deficiency must be excluded first because folate alone will correct anemia while masking and potentially accelerating B12-deficient subacute combined degeneration<ref name="folvite-label">FDA Prescribing Information, folic acid tablets, current revision. https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/06006slr027_folvite_lbl.pdf</ref>.
}}

== References ==
<references />

Folic Acid - Revision history

MDElliottMD: home-claude category backfill (parser-claude gap closure)

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #94