MDElliottMD: home-claude category backfill (parser-claude gap closure)

2026-05-23T10:43:29Z

home-claude category backfill (parser-claude gap closure)

← Older revision		Revision as of 10:43, 23 May 2026
Line 21:		Line 21:
	== References ==		== References ==
	<references />		<references />
			[[Category:Loop diuretics]]
			[[Category:Diuretics]]

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #29

2026-05-23T03:34:49Z

parser-claude batch MedTemplate pre-fill, Top 300 #29

New page

{{MedTemplate
| generic = Furosemide
| brand = Lasix
| structure =
| classes = [[:Category:Loop_diuretics|Loop diuretic]], [[:Category:Diuretics|Diuretic]]
| uses = <vote slug="chf-volume-overload-use">Volume overload in heart failure</vote>, <vote slug="pulmonary-edema-use">Acute pulmonary edema</vote>, <vote slug="ascites-use">Ascites in cirrhosis</vote>, <vote slug="ckd-edema-use">Edema in CKD</vote>, <vote slug="hypercalcemia-use">Adjunct in hypercalcemia</vote>, <vote slug="hypertension-use">Hypertension (specific cases)</vote>
| starting_dose = 20-40 mg PO/IV; titrate by clinical response. In diuretic-resistant heart failure or CKD, doses to 200 mg or higher may be needed
| preparations = 20, 40, 80 mg tablets; 10 mg/mL oral solution; 10 mg/mL IV
| fda_max = 600 mg/d typical practical ceiling in heart failure
| pill_id =
| routes = Oral, IV, IM
| onset = IV: 5 minutes; PO: 30-60 minutes
| duration = IV: ~2 hours; PO: 6-8 hours
| halflife = 1.5-2 hours (longer in renal failure)<ref name="lasix-label">FDA Prescribing Information, Lasix (furosemide), Sanofi-Aventis, current revision. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/016273s069lbl.pdf</ref>
| bioavailability = ~50% (oral; highly variable, 10-100%, hence the standard 1:2 IV-to-PO conversion)<ref name="lasix-label" />
| pregnancy = Avoid where possible; can reduce uteroplacental perfusion and produce neonatal electrolyte disturbance. Reserved for compelling indications.{{citation needed}}
| legal = [[USLegal:Prescription only|Rx-only]] in US
| mechanism = <vote slug="furosemide-mech-claim">Furosemide blocks the Na+/K+/2Cl- cotransporter (NKCC2) on the apical membrane of thick ascending limb cells, abolishing the medullary osmotic gradient and producing brisk natriuresis, kaliuresis, and free-water clearance.</vote> Loop diuretics are the most potent diuretics in routine clinical use because the ascending limb reabsorbs ~25% of filtered sodium. Ototoxicity (especially with rapid IV bolus), hypokalemic metabolic alkalosis, hyperuricemia, and gout flare are the characteristic side effects<ref name="lasix-label" />.
}}

== References ==
<references />

Furosemide - Revision history

MDElliottMD: home-claude category backfill (parser-claude gap closure)

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #29