MDElliottMD: home-claude category backfill (parser-claude gap closure)

2026-05-23T10:43:32Z

home-claude category backfill (parser-claude gap closure)

← Older revision		Revision as of 10:43, 23 May 2026
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	== References ==		== References ==
	<references />		<references />
			[[Category:H1 receptor antagonists]]
			[[Category:Antihistamines]]

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #105

2026-05-23T03:46:15Z

parser-claude batch MedTemplate pre-fill, Top 300 #105

New page

{{MedTemplate
| generic = Loratadine
| brand = Claritin, Alavert, Tavist ND
| structure =
| classes = [[:Category:H1_receptor_antagonists|Histamine H1 receptor antagonist (second-generation)]], [[:Category:Antihistamines|Antihistamine]]
| uses = <vote slug="allergic-rhinitis-use">Allergic rhinitis</vote>, <vote slug="chronic-urticaria-use">Chronic idiopathic urticaria</vote>
| starting_dose = 10 mg PO once daily
| preparations = 10 mg tablets; 5 mg ODT and chewables; 1 mg/mL oral syrup; combo Claritin-D (with pseudoephedrine, behind-counter)
| fda_max = 10 mg/d (adults)
| pill_id =
| routes = Oral
| onset = 1-3 hours (slower onset than cetirizine; symptom relief somewhat less)
| duration = 24 hours
| halflife = ~8 hours (parent); ~28 hours (desloratadine, the active metabolite, marketed separately as Clarinex)<ref name="claritin-label">FDA Prescribing Information, Claritin (loratadine), Bayer, current revision. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/019835s050lbl.pdf</ref>
| bioavailability = High (oral; food prolongs absorption modestly)<ref name="claritin-label" />
| pregnancy = Generally considered safe; widely used. Loratadine and cetirizine are the most-recommended 2nd-gen H1s in pregnancy and lactation.{{citation needed}}
| legal = OTC in US
| mechanism = <vote slug="loratadine-mech-claim">Loratadine is a selective peripheral H1 receptor antagonist with very limited blood-brain barrier penetration, producing antihistaminic effect without significant sedation; it is metabolized by CYP3A4 and CYP2D6 to desloratadine, the longer-half-life active metabolite.</vote> Less reliably anticholinergic than first-generation H1s; minimal antiemetic effect. Desloratadine (Clarinex) is the active enantiomer-of-metabolite version marketed as a Rx alternative.
}}

== References ==
<references />

Loratadine - Revision history

MDElliottMD: home-claude category backfill (parser-claude gap closure)

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #105