Meclizine - Revision history

MDElliottMD: parser-claude: Meclizine MedTemplate refill, Top 300 stub upgrade

2026-05-23T07:04:23Z

parser-claude: Meclizine MedTemplate refill, Top 300 stub upgrade

← Older revision		Revision as of 07:04, 23 May 2026
Line 1:		Line 1:
	{{MedTemplate		{{MedTemplate
	\| generic = Meclizine		\| generic = Meclizine
	\| brand = Antivert		\| brand = Antivert (Rx), Bonine (OTC), Dramamine Less Drowsy (OTC)
	\| structure =		\| structure =
	\| classes = ~~Antihistamine~~, Antiemetic		\| classes = [[:Category:Antihistamines\|First-generation antihistamine (piperazine)]], [[:Category:Antiemetics\|Antiemetic]], [[:Category:Antivertigo medicines\|Antivertigo medicine]]
	\| ~~mechanism = H1 receptor antagonist~~		\| uses = <vote slug="motion-sickness-use">Motion sickness prevention (OTC and FDA)</vote>, <vote slug="vertigo-use">Vertigo (FDA)</vote>, <vote slug="meniere-disease-symptomatic-use">Symptomatic Meniere disease (off-label)</vote>
	\| uses =		\| starting_dose = Motion sickness: 25-50 mg PO 1 hour before travel, repeat every 24 hours as needed. Vertigo: 25-100 mg/day divided
	\| starting_dose =		\| preparations = Tablets 12.5, 25 mg; chewable tablets 25 mg
	\| preparations =		\| fda_max = 100 mg/day (vertigo)
	\| fda_max =		\| pill_id =
	\| routes =		\| routes = Oral
	\| onset =		\| onset = ~1 hour
	\| duration =		\| duration = 12-24 hours (long for an antihistamine)
	\| halflife =		\| halflife = ~6 hours<ref name="antivert-label">FDA Prescribing Information, Antivert (meclizine hydrochloride), Pfizer/various, current revision. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/010721s059lbl.pdf</ref>
	\| bioavailability =		\| bioavailability = ~25% (oral)<ref name="antivert-label" />
	\| pregnancy =		\| pregnancy = Older agent with substantial use experience; observational signals reassuring for first-trimester exposure.{{citation needed}}
	\| legal =		\| legal = [[USLegal:Over-the-counter\|OTC]] as Bonine and Dramamine Less Drowsy; [[USLegal:Prescription only\|Rx-only]] as Antivert
	\| ~~intro =~~		\| mechanism = <vote slug="meclizine-mech-claim">First-generation H1 receptor antagonist with central nervous system penetration. Additional moderate anticholinergic activity contributes to the antiemetic and antivertigo effects, acting at central vestibular pathways and the chemoreceptor trigger zone of the area postrema. Less sedating than diphenhydramine on a milligram basis, but more sedating than the second-generation non-sedating antihistamines.</vote> Anticholinergic burden (dry mouth, blurred vision, urinary retention, cognitive effects) is the principal adverse-event concern and the basis for Beers-list cautions in elderly patients<ref name="antivert-label" />.
	\| ~~pharmacokinetics =~~
	\| ~~pharmacodynamics~~ =
	~~\| indications~~ =
	~~\| dosing =~~
	\| effects =
	~~\| interactions =~~ <~~pharmaInteractions~~/>
	~~\| pregnancy_details =~~
	~~\| monitoring =~~
	~~\| counseling =~~
	~~\| anecdotes =~~
	~~\| seealso =~~
	~~\| references~~ =
	}}		}}

			== References ==
			<references />

	[[Category:Antihistamines]]		[[Category:Antihistamines]]
	[[Category:~~First-generation antihistamines~~]]		[[Category:Antiemetics]]
			[[Category:Antivertigo medicines]]

MDElliottMD: Comprehensive categorization: +First-generation antihistamines

2026-05-15T18:42:19Z

Comprehensive categorization: +First-generation antihistamines

← Older revision		Revision as of 18:42, 15 May 2026
Line 32:		Line 32:

	[[Category:Antihistamines]]		[[Category:Antihistamines]]
			[[Category:First-generation antihistamines]]

MDElliottMD: Pharmacopedia: add

2026-05-14T03:30:58Z

Pharmacopedia: add <pharmaInteractions/>

← Older revision		Revision as of 03:30, 14 May 2026
Line 22:		Line 22:
	\| dosing =		\| dosing =
	\| effects =		\| effects =
	\| interactions =		\| interactions = <pharmaInteractions/>
	\| pregnancy_details =		\| pregnancy_details =
	\| monitoring =		\| monitoring =

MDElliottMD: Pharmacopedia: remove contraindications parameter

2026-05-14T02:40:40Z

Pharmacopedia: remove contraindications parameter

← Older revision		Revision as of 02:40, 14 May 2026
Line 22:		Line 22:
	\| dosing =		\| dosing =
	\| effects =		\| effects =
	~~\| contraindications =~~
	\| interactions =		\| interactions =
	\| pregnancy_details =		\| pregnancy_details =

MDElliottMD: Added empty fda_max parameter to MedTemplate call

2026-05-13T02:32:56Z

Added empty fda_max parameter to MedTemplate call

← Older revision		Revision as of 02:32, 13 May 2026
Line 8:		Line 8:
	\| starting_dose =		\| starting_dose =
	\| preparations =		\| preparations =
			\| fda_max =
	\| routes =		\| routes =
	\| onset =		\| onset =
Line 32:		Line 33:

	[[Category:Antihistamines]]		[[Category:Antihistamines]]

MDElliottMD: Expand stub to full MedTemplate parameter set

2026-05-13T01:00:00Z

Expand stub to full MedTemplate parameter set

@@ Line 1: / Line 1: @@
 {{MedTemplate
-| generic           = Meclizine
+| generic            = Meclizine
-| brand             = Antivert
+| brand              = Antivert
-| classes           = Antihistamine, Antiemetic
+| structure          =
-| mechanism         = H1 receptor antagonist
+| classes            = Antihistamine, Antiemetic
 }}
 [[Category:Antihistamines]]

MDElliottMD: Auto-created stub

2026-05-13T00:00:00Z

Auto-created stub

New page

{{MedTemplate
| generic = Meclizine
| brand = Antivert
| classes = Antihistamine, Antiemetic
| mechanism = H1 receptor antagonist
}}
[[Category:Antihistamines]]