https://pharmacopedia.wiki/index.php?action=history&feed=atom&title=Receptor%3A5-HT2A 2026-05-28T07:32:53Z Revision history for this page on the wiki MediaWiki 1.46.0-beta https://pharmacopedia.wiki/index.php?title=Receptor:5-HT2A&diff=5667&oldid=prev 2026-05-22T03:01:06Z

<p>Create receptor entity seed stub</p> <p><b>New page</b></p><div>&#039;&#039;&#039;5-HT2A&#039;&#039;&#039; is a G protein-coupled [[Serotonin|serotonin]] receptor and the most extensively studied member of the 5-HT2 receptor family, which signals predominantly through Gq/11 proteins and [[Phospholipase C|phospholipase C]].&lt;ref name=&quot;hoyer2002&quot;&gt;Hoyer D, Hannon JP, Martin GR. Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacology, Biochemistry, and Behavior. 2002 Apr;71(4):533-554. PMID: 11888546.&lt;/ref&gt; It is densely expressed on cortical pyramidal neurons and is the principal molecular target of the serotonergic (&quot;classic&quot;) psychedelics, including [[LSD]], [[Psilocybin|psilocybin]], [[DMT]], and [[2C-B]], whose characteristic effects depend on 5-HT2A agonism.&lt;ref name=&quot;nichols2016&quot;&gt;Nichols DE. Psychedelics. Pharmacological Reviews. 2016 Apr;68(2):264-355. PMID: 26841800.&lt;/ref&gt; 5-HT2A antagonism also contributes to the pharmacology of the second-generation [[:Category:Neuroleptics|neuroleptics]].<br /> <br /> This page is a seed stub.<br /> <br /> == References ==<br /> &lt;references/&gt;<br /> <br /> [[Category:Receptors]]</div>

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