https://pharmacopedia.wiki/index.php?action=history&feed=atom&title=Receptor%3A5-HT2C 2026-05-28T08:29:07Z Revision history for this page on the wiki MediaWiki 1.46.0-beta https://pharmacopedia.wiki/index.php?title=Receptor:5-HT2C&diff=5669&oldid=prev 2026-05-22T03:01:07Z

<p>Create receptor entity seed stub</p> <p><b>New page</b></p><div>&#039;&#039;&#039;5-HT2C&#039;&#039;&#039; is a G protein-coupled [[Serotonin|serotonin]] receptor of the 5-HT2 family, signaling through Gq/11 proteins and [[Phospholipase C|phospholipase C]], and is expressed almost exclusively in the central nervous system, where it contributes to the regulation of appetite, mood, and locomotor activity.&lt;ref name=&quot;hoyer2002&quot;&gt;Hoyer D, Hannon JP, Martin GR. Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacology, Biochemistry, and Behavior. 2002 Apr;71(4):533-554. PMID: 11888546.&lt;/ref&gt; 5-HT2C agonism suppresses appetite and was the mechanism of the anorectic medicine [[Lorcaserin|lorcaserin]], while 5-HT2C antagonism is one contributor to the weight gain associated with several [[:Category:Neuroleptics|neuroleptics]].<br /> <br /> This page is a seed stub.<br /> <br /> == References ==<br /> &lt;references/&gt;<br /> <br /> [[Category:Receptors]]</div>

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