MDElliottMD: home-claude category backfill (parser-claude gap closure)

2026-05-23T10:43:43Z

home-claude category backfill (parser-claude gap closure)

← Older revision		Revision as of 10:43, 23 May 2026
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	== References ==		== References ==
	<references />		<references />
			[[Category:Anticaries agents]]
			[[Category:Trace elements]]

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #264

2026-05-23T04:19:16Z

parser-claude batch MedTemplate pre-fill, Top 300 #264

New page

{{MedTemplate
| generic = Sodium fluoride
| brand = Many; topical professional/OTC and Rx oral
| structure =
| classes = [[:Category:Anticaries_agents|Anticaries agent]], [[:Category:Trace_elements|Trace element]]
| uses = <vote slug="caries-prevention-use">Dental caries prevention</vote>, <vote slug="dentin-hypersensitivity-use">Dentin hypersensitivity (high-concentration topical)</vote>
| starting_dose = OTC dentifrice/rinse 0.05-0.5% fluoride daily; Rx 1.1% sodium fluoride toothpaste/gel daily; supplements (where local water non-fluoridated) age-titrated 0.25-1 mg/d
| preparations = Toothpaste, rinse, gel, varnish (topical); 0.25, 0.5, 1 mg tablets and drops (Rx supplements where appropriate)
| fda_max = Topical: per formulation; oral supplement age-dependent
| pill_id =
| routes = Topical, oral
| onset = Caries reduction over months to years of consistent use
| duration = Hours per topical application
| halflife = ~6 hours plasma; long bone retention
| bioavailability = Topical: local effect on enamel; systemic supplementation has high oral bioavailability with skeletal accumulation
| pregnancy = Safe at routine fluoride levels.{{citation needed}}
| legal = OTC (most dentifrice and rinse) and [[USLegal:Prescription only|Rx-only]] (high-concentration paste/gel, supplements) in US
| mechanism = <vote slug="fluoride-mech-claim">Topical fluoride is incorporated into enamel hydroxyapatite to form fluorapatite, which is more resistant to acid demineralization; it also inhibits cariogenic bacterial enolase and glycolysis, reducing acid production.</vote> Systemic fluoride (water fluoridation, supplements during tooth development) is incorporated into developing enamel, providing pre-eruptive caries protection. '''Dental fluorosis''' (mottling) is the chief sign of excess during tooth development; skeletal fluorosis is the chronic systemic toxicity at very high cumulative doses.
}}

== References ==
<references />

Sodium Fluoride - Revision history

MDElliottMD: home-claude category backfill (parser-claude gap closure)

MDElliottMD: parser-claude batch MedTemplate pre-fill, Top 300 #264