Initial genital herpes 400 mg PO TID × 7-10 days; episodic 800 mg TID × 2 days; suppression 400 mg BID; herpes zoster 800 mg 5×/day × 7 days; HSV encephalitis 10 mg/kg IV q8h × 14-21 days
preparations
String
200, 400, 800 mg tablets; 200 mg capsules; 200 mg/5 mL suspension; 500, 1000 mg IV vials; 5% cream and ointment (topical)
fda_max
String
Indication-specific; high-dose IV regimens for encephalitis or disseminated disease
pill_id
Text
routes
List of String, delimiter: ,
Oral • IV • topical
onset
String
Symptom relief within 24-48 hours of starting episodic treatment
duration
String
8 hours per oral dose
halflife
String
~3 hours; significantly prolonged in renal impairment'"`UNIQ--ref-0000090F-QINU`"'
bioavailability
String
~20% (oral; valacyclovir prodrug raises this to ~55%)'"`UNIQ--ref-00000910-QINU`"'
pregnancy
String
Widely used in pregnancy for HSV/VZV indications; reassuring registry data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
