1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Amiodarone |
| brand | String | Cordarone, Pacerone, Nexterone (IV) |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Antiarrhythmics|Antiarrhythmic (Vaughan-Williams class III)]] • [[:Category:Cardiovascular_agents|Cardiovascular agent]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-00000CB0-QINU`"', '"`UNIQ--vote-00000CB1-QINU`"', '"`UNIQ--vote-00000CB2-QINU`"' |
| starting_dose | String | Oral load 800-1600 mg/d in divided doses for 1-3 weeks, then 600-800 mg/d for 1 month, then 200-400 mg/d maintenance; IV 150 mg over 10 min then 1 mg/min for 6 hours then 0.5 mg/min |
| preparations | String | 100, 200, 400 mg tablets; 50 mg/mL IV (with polysorbate 80 in older formulations causing hypotension); 1.5 mg/mL Nexterone IV (PVC-free, lower hypotension risk) |
| fda_max | String | Oral maintenance 400 mg/d typical; higher in refractory cases |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral • IV |
| onset | String | IV: minutes; oral: weeks to load |
| duration | String | Weeks after discontinuation (extremely long half-life) |
| halflife | String | ~58 days (parent); ~61 days (desethylamiodarone, active metabolite)'"`UNIQ--ref-00000CB3-QINU`"' |
| bioavailability | String | ~50% (oral; highly variable)'"`UNIQ--ref-00000CB4-QINU`"' |
| pregnancy | String | Generally avoided; fetal goiter/hypothyroidism risk (iodine load). Used only for life-threatening arrhythmia.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US. Carries '''Boxed Warnings''' for pulmonary toxicity (interstitial pneumonitis, fibrosis), hepatotoxicity, and proarrhythmia'"`UNIQ--ref-00000CB5-QINU`"' |
