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Page values for "Buspirone"

"Medicines" values

1 row is stored for this page
FieldField typeValue
genericStringBuspirone
brandStringBuspar (US brand discontinued; generic widely available)
structureFile
classesList of String, delimiter: ,[[:Category:Anxiolytics|Anxiolytic]] [[:Category:Azapirones|Azapirone]] [[:Category:Serotonin 5-HT1A partial agonists|Serotonin 5-HT1A partial agonist]]
mechanismString
usesString'"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"', '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"'
starting_doseString5 mg PO TID or 7.5 mg PO BID; titrate by 5 mg every 2-3 days to clinical effect, commonly 30-60 mg/day divided BID-TID
preparationsStringTablets 5, 7.5, 10, 15, 30 mg (the 15 and 30 mg tablets are scored for halving and quartering)
fda_maxString60 mg/day
pill_idText
routesList of String, delimiter: ,Oral
onsetString'''Anxiolytic effect emerges over 2-4 weeks'''; buspirone does NOT work for acute anxiety, which is the central teaching point and the most common cause of treatment failure
durationString~8 hours (TID dosing)
halflifeStringBuspirone 2-3 hours; 1-PP active metabolite 4-6 hours'"`UNIQ--ref-0000001D-QINU`"'
bioavailabilityString~4% (extensive first-pass metabolism)'"`UNIQ--ref-0000001E-QINU`"'
pregnancyStringLimited human data; older agent with substantial use experience and no clear teratogenic signal.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup>
legalString[[USLegal:Prescription only|Rx-only]] in US. Not a controlled substance, which is a meaningful clinical advantage over benzodiazepine alternatives for chronic anxiety'"`UNIQ--ref-0000001F-QINU`"'