1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Citalopram |
| brand | String | Celexa |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:SSRIs|Selective serotonin reuptake inhibitor (SSRI)]] • [[:Category:Antidepressants|Antidepressant]] |
| mechanism | String | '"`UNIQ--vote-0000001D-QINU`"' CYP2C19 + CYP3A4 metabolism, with CPIC PGx guidance: poor CYP2C19 metabolizers have ~3-fold higher exposure and benefit from a lower starting dose; ultrarapid metabolizers may have inadequate response'"`UNIQ--ref-0000001E-QINU`"'. |
| uses | String | '"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"' |
| starting_dose | String | 20 mg PO once daily; titrate to 40 mg/day after 1 week if tolerated. Elderly (>60) and hepatic impairment: 20 mg/day ceiling |
| preparations | String | Tablets 10, 20, 40 mg; oral solution 10 mg/5 mL |
| fda_max | String | '''20 mg/day in adults >60 years''' per FDA's 2011-2012 QT-prolongation warning; 40 mg/day in adults ≤60 |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | Antidepressant effect over 1-2 weeks; full clinical effect 4-6 weeks |
| duration | String | 24 hours (once-daily dosing) |
| halflife | String | ~35 hours'"`UNIQ--ref-00000026-QINU`"' |
| bioavailability | String | ~80% (oral)'"`UNIQ--ref-00000027-QINU`"' |
| pregnancy | String | Observational signal for persistent pulmonary hypertension of the newborn (small absolute risk) and neonatal adaptation syndrome with third-trimester exposure.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US. Carries the antidepressant '''Boxed Warning''' for suicidality in children, adolescents, and young adults'"`UNIQ--ref-00000028-QINU`"' |
