75 mg PO once daily for maintenance; 300-600 mg PO loading dose in ACS or before PCI
preparations
String
75 mg, 300 mg tablets
fda_max
String
75 mg/d maintenance (loading doses are single events)
pill_id
Text
routes
List of String, delimiter: ,
Oral
onset
String
Antiplatelet effect within 2 hours of a loading dose; steady-state at 5-7 days of maintenance dosing
duration
String
5-7 days (platelet lifespan; irreversible receptor binding)
halflife
String
~6 hours (parent); active metabolite very short-lived but produces irreversible platelet effect'"`UNIQ--ref-000002C4-QINU`"'
bioavailability
String
~50% (oral)'"`UNIQ--ref-000002C5-QINU`"'
pregnancy
String
Limited data; weigh against alternatives (aspirin) where feasible.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
