10 mg PO once daily in the morning; 5 mg starting in heart failure
preparations
String
5 mg, 10 mg tablets
fda_max
String
10 mg/d
pill_id
Text
routes
List of String, delimiter: ,
Oral
onset
String
Glycosuria within hours; HbA1c effect at 12 weeks; CV/renal benefits over months
duration
String
24 hours
halflife
String
~12.9 hours'"`UNIQ--ref-00000552-QINU`"'
bioavailability
String
~78% (oral; high-fat meal modestly reduces but is not clinically significant)'"`UNIQ--ref-00000553-QINU`"'
pregnancy
String
Avoid in second and third trimesters; fetal SGLT2 inhibition disrupts kidney development.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
