50 mg PO once daily ('''no titration required''', distinguishing it favorably from venlafaxine)
preparations
String
ER tablets 25, 50, 100 mg
fda_max
String
50 mg/day (no efficacy benefit shown for higher doses despite the 100 mg strength being available)
pill_id
Text
routes
List of String, delimiter: ,
Oral
onset
String
Antidepressant effect emerges over 1-2 weeks
duration
String
24 hours
halflife
String
~11 hours'"`UNIQ--ref-0000001A-QINU`"'
bioavailability
String
~80% (oral)'"`UNIQ--ref-0000001B-QINU`"'
pregnancy
String
Observational signal for neonatal adaptation syndrome with late-pregnancy exposure (SNRI class effect).<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
legal
String
[[USLegal:Prescription only|Rx-only]] in US. Carries the antidepressant '''Boxed Warning''' for suicidality in children, adolescents, and young adults'"`UNIQ--ref-0000001C-QINU`"'
