1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Diclofenac (sodium, potassium, epolamine; multiple salt forms) |
| brand | String | Voltaren (IR oral, topical gel), Cataflam (potassium IR), Cambia (oral powder, migraine), Zorvolex (low-dose), Pennsaid (topical 2% solution), Flector (transdermal patch), Solaraze (3% gel for actinic keratosis) |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:NSAIDs|Non-steroidal anti-inflammatory (NSAID)]] • [[:Category:Analgesics|Analgesic]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"', '"`UNIQ--vote-00000026-QINU`"', '"`UNIQ--vote-00000027-QINU`"', '"`UNIQ--vote-00000028-QINU`"' |
| starting_dose | String | IR oral 50 mg PO TID or 75 mg BID. Voltaren 1% gel: apply 2-4 g to affected area QID. Pennsaid 2%: 40 drops to knee BID. Flector patch: every 12 hours |
| preparations | String | IR tablets 25, 50 mg; ER tablets 100 mg; Cataflam IR 50 mg; Zorvolex 18, 35 mg; Voltaren gel 1%; Pennsaid 2% topical solution; Flector transdermal patch; Solaraze 3% gel; Cambia oral powder 50 mg |
| fda_max | String | 150 mg/day (oral); use lowest effective dose for shortest duration per FDA NSAID class guidance |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral • topical • transdermal • oral powder (Cambia for migraine) |
| onset | String | 30-60 minutes (oral); slower for topical |
| duration | String | 6-8 hours (IR oral); 12-24 hours (ER) |
| halflife | String | 1-2 hours (parent compound)'"`UNIQ--ref-00000029-QINU`"' |
| bioavailability | String | ~50-60% (oral; substantial first-pass metabolism)'"`UNIQ--ref-0000002A-QINU`"' |
| pregnancy | String | Avoid from 20 weeks gestation onward per FDA's 2020 expanded NSAID warning (fetal renal dysfunction, oligohydramnios); contraindicated from 30 weeks (risk of premature ductus arteriosus closure)'"`UNIQ--ref-0000002B-QINU`"' |
| legal | String | [[USLegal:Prescription only|Rx-only]] for oral and most topical formulations in US; Voltaren Arthritis Pain 1% gel switched to [[USLegal:Over-the-counter|OTC]] in 2020 |
