10 mg PO once daily in the morning; may titrate to 25 mg for additional glycemic effect
preparations
String
10 mg, 25 mg tablets
fda_max
String
25 mg/d
pill_id
Text
routes
List of String, delimiter: ,
Oral
onset
String
Glycosuria within hours; HbA1c effect at 12 weeks; cardiovascular and renal benefits over months
duration
String
24 hours
halflife
String
~12.4 hours'"`UNIQ--ref-0000027C-QINU`"'
bioavailability
String
High (oral; not affected by food, but typically given with the morning meal)'"`UNIQ--ref-0000027D-QINU`"'
pregnancy
String
Avoid in second and third trimesters; fetal SGLT2 inhibition disrupts kidney development.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
