'"`UNIQ--vote-00000255-QINU`"' Less potent and shorter-acting than PPIs but with faster on-effect; suitable for on-demand acid suppression. Largely renally cleared; dose-adjust in renal impairment to avoid CNS effects (confusion in elderly)'"`UNIQ--ref-00000256-QINU`"'.
10 mg, 20 mg, 40 mg tablets; chewables; 40 mg/5 mL oral suspension; 10 mg/mL IV
fda_max
String
160 mg/d (Zollinger-Ellison); 80 mg/d for routine indications
pill_id
Text
routes
List of String, delimiter: ,
Oral • IV
onset
String
1 hour PO; minutes IV
duration
String
6-12 hours
halflife
String
2.5-3.5 hours; longer in renal impairment'"`UNIQ--ref-0000025B-QINU`"'
bioavailability
String
40-45% (oral; not significantly affected by food)'"`UNIQ--ref-0000025C-QINU`"'
pregnancy
String
Generally considered safe; widely used. Cleared in lactation at low levels.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
legal
String
OTC (10-20 mg) and [[USLegal:Prescription only|Rx-only]] (higher doses) in US
