Page values for "Hydralazine"

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"Medicines" values

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Field	Field type	Value
generic	`String`	Hydralazine
brand	`String`	Apresoline (historical); mostly generic; combination with isosorbide dinitrate marketed as BiDil for self-identified Black patients with HFrEF
structure	`File`
classes	List of `String`, delimiter: `,`	[[:Category:Direct_vasodilators\|Direct arteriolar vasodilator]] • [[:Category:Antihypertensives\|Antihypertensive]]
mechanism	`String`
uses	`String`	'"`UNIQ--vote-00000683-QINU`"', '"`UNIQ--vote-00000684-QINU`"', '"`UNIQ--vote-00000685-QINU`"', '"`UNIQ--vote-00000686-QINU`"'
starting_dose	`String`	PO 10 mg QID; IV 5-10 mg every 20-30 minutes for hypertensive emergency
preparations	`String`	10, 25, 50, 100 mg tablets; 20 mg/mL IV
fda_max	`String`	300 mg/d typical practical limit (toxicity rises sharply above)
pill_id	`Text`
routes	List of `String`, delimiter: `,`	Oral • IV • IM
onset	`String`	IV: 5-20 minutes; PO: 30-60 minutes
duration	`String`	IV: 1-4 hours; PO: 3-8 hours
halflife	`String`	3-7 hours (slow acetylators) vs 1-3 hours (rapid acetylators) via NAT2 polymorphism'"`UNIQ--ref-00000687-QINU`"'
bioavailability	`String`	~25-50% (oral; substantial first-pass via NAT2 acetylation, phenotype-dependent)'"`UNIQ--ref-00000688-QINU`"'
pregnancy	`String`	One of the historically preferred IV agents for severe hypertension in pregnancy alongside labetalol and nifedipine.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed\|citation needed]]]</sup>
legal	`String`	[[USLegal:Prescription only\|Rx-only]] in US