200-400 mg PO daily; '''dose by actual body weight ≤5 mg/kg/d''' to reduce retinopathy risk (AAO 2016 guideline)
preparations
String
200 mg tablets; 100 mg/5 mL suspension
fda_max
String
400 mg/d typical maintenance; weight-adjusted ceiling per ophthalmology guidance
pill_id
Text
routes
List of String, delimiter: ,
Oral
onset
String
Rheumatologic effect at 6-12 weeks
duration
String
Weeks (long half-life)
halflife
String
~40 days (terminal; reflects extensive tissue distribution)'"`UNIQ--ref-000007EC-QINU`"'
bioavailability
String
70-75% (oral)'"`UNIQ--ref-000007ED-QINU`"'
pregnancy
String
Long-considered safe in pregnancy for lupus and other rheumatologic indications; benefits typically outweigh.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
