1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Isosorbide (dinitrate, mononitrate) |
| brand | String | Imdur (mononitrate ER), Isordil (dinitrate); generics; with hydralazine as BiDil for HFrEF in self-identified Black patients |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Nitrates|Organic nitrate]] • [[:Category:Vasodilators|Vasodilator]] • [[:Category:Antianginals|Antianginal]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-0000145E-QINU`"', '"`UNIQ--vote-0000145F-QINU`"', '"`UNIQ--vote-00001460-QINU`"' |
| starting_dose | String | Isosorbide mononitrate ER: 30-60 mg PO once daily in the morning, titrate to 120-240 mg/d; isosorbide dinitrate IR: 5-20 mg PO TID with a 12-14 hour nitrate-free interval to prevent tolerance |
| preparations | String | Mononitrate 10, 20 mg IR; 30, 60, 120 mg ER; dinitrate 5, 10, 20, 30, 40 mg IR and ER |
| fda_max | String | 240 mg/d (mononitrate ER); 160 mg/d (dinitrate) |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral • sublingual (dinitrate) |
| onset | String | SL: 2-5 minutes; PO mononitrate: 30-60 minutes |
| duration | String | Mononitrate ER: 12-24 hours; dinitrate IR: 4-6 hours |
| halflife | String | Mononitrate ~5 hours; dinitrate ~1 hour'"`UNIQ--ref-00001461-QINU`"' |
| bioavailability | String | Mononitrate ~100% (no first-pass; the principal advantage over dinitrate); dinitrate ~20%'"`UNIQ--ref-00001462-QINU`"' |
| pregnancy | String | Limited data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US |
