Page values for "Ketoconazole"

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"Medicines" values

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Field	Field type	Value
generic	`String`	Ketoconazole
brand	`String`	Nizoral (oral discontinued in US for most fungal indications; topical still widely available)
structure	`File`
classes	List of `String`, delimiter: `,`	[[:Category:Antifungals\|Antifungal (imidazole)]] • [[:Category:Topical_antifungals\|Topical antifungal]]
mechanism	`String`
uses	`String`	'"`UNIQ--vote-00000884-QINU`"', '"`UNIQ--vote-00000885-QINU`"', '"`UNIQ--vote-00000886-QINU`"', '"`UNIQ--vote-00000887-QINU`"'
starting_dose	`String`	Topical 2% shampoo twice weekly for seborrheic dermatitis or tinea versicolor; oral use restricted by 2013 FDA action to indications where alternatives have failed
preparations	`String`	1% (OTC), 2% (Rx) shampoo; 2% cream; 2% gel; 200 mg oral tablet (rarely used now)
fda_max	`String`	Topical: regimen-specific; oral: 400 mg/d in remaining specialty indications
pill_id	`Text`
routes	List of `String`, delimiter: `,`	Topical (cream • shampoo • gel); oral (restricted)
onset	`String`	Topical hours; oral days
duration	`String`	Hours per application (topical); 24 hours (oral)
halflife	`String`	Topical: not meaningfully described; oral 2-8 hours'"`UNIQ--ref-00000888-QINU`"'
bioavailability	`String`	Topical: minimal systemic; oral: pH-dependent, requires gastric acid'"`UNIQ--ref-00000889-QINU`"'
pregnancy	`String`	Topical generally safe; oral avoided.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed\|citation needed]]]</sup>
legal	`String`	OTC (1% shampoo) and [[USLegal:Prescription only\|Rx-only]] (higher strengths, oral) in US. Oral form carries a '''Boxed Warning''' for hepatotoxicity and is restricted by FDA to refractory fungal infections where no alternatives are available