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Page values for "Labetalol"

"Medicines" values

1 row is stored for this page
FieldField typeValue
genericStringLabetalol
brandStringTrandate, Normodyne (discontinued in US)
structureFile
classesList of String, delimiter: ,[[:Category:Beta blockers|Combined alpha-1 and non-selective beta blocker]] [[:Category:Antihypertensives|Antihypertensive]]
mechanismString'"`UNIQ--vote-00000015-QINU`"' The favorable pregnancy safety profile and the dual mechanism support its first-line role in pregnancy-associated hypertension and in hypertensive emergencies where rapid, controllable BP reduction is needed'"`UNIQ--ref-00000016-QINU`"'.
usesString'"`UNIQ--vote-00000017-QINU`"', '"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"'
starting_doseStringOral: 100 mg PO BID, titrate to 400 mg BID. IV: 20 mg over 2 minutes, repeat 40-80 mg every 10 minutes as needed (maximum cumulative 300 mg); continuous infusion 2 mg/minute
preparationsStringTablets 100, 200, 300 mg; injection 5 mg/mL
fda_maxString2400 mg/day (oral); 300 mg total per IV bolus dosing series
pill_idText
routesList of String, delimiter: ,Oral intravenous
onsetStringBP effect within hours (oral); 5-10 minutes (IV)
durationString8-12 hours (oral); 4-6 hours (IV)
halflifeString~6-8 hours'"`UNIQ--ref-0000001A-QINU`"'
bioavailabilityString~25% (oral; extensive first-pass)'"`UNIQ--ref-0000001B-QINU`"'
pregnancyString'''Among the safest antihypertensives in pregnancy''', recommended for chronic hypertension during pregnancy and first-line for severe hypertension in preeclampsia and eclampsia'"`UNIQ--ref-0000001C-QINU`"'
legalString[[USLegal:Prescription only|Rx-only]] in US