Hypothyroidism: 5-25 mcg PO daily (start low, titrate slowly); myxedema coma: 5-20 mcg IV q4-12h with T4 loading
preparations
String
5, 25, 50 mcg tablets (Cytomel); 10 mcg/mL IV (Triostat)
fda_max
String
100 mcg/d typical
pill_id
Text
routes
List of String, delimiter: ,
Oral • IV
onset
String
Hours (faster than T4); peak biologic activity 24-48 hours
duration
String
24-72 hours
halflife
String
~1 day (much shorter than T4's ~7 days)'"`UNIQ--ref-0000149D-QINU`"'
bioavailability
String
~95% (oral)'"`UNIQ--ref-0000149E-QINU`"'
pregnancy
String
T4 (levothyroxine) is the first-line in pregnancy; T3 is rarely needed.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
