1 row is stored for this page
Field Field type Value generic String Losartan brand String Cozaar structure File classes List of String , delimiter: , [[:Category:Angiotensin_receptor_blockers|Angiotensin receptor blocker (ARB)]] • [[:Category:Antihypertensives|Antihypertensive]] mechanism String '"`UNIQ--vote-000000B6-QINU`"' Active metabolite EXP3174 is ~10-40-fold more potent than the parent and accounts for most of the antihypertensive effect; CYP2C9 polymorphism affects conversion'"`UNIQ--ref-000000B7-QINU`"'. uses String '"`UNIQ--vote-000000B8-QINU`"', '"`UNIQ--vote-000000B9-QINU`"', '"`UNIQ--vote-000000BA-QINU`"', '"`UNIQ--vote-000000BB-QINU`"' starting_dose String 50 mg PO daily (25 mg in volume depletion or hepatic impairment) preparations String 25 mg, 50 mg, 100 mg tablets fda_max String 100 mg/d pill_id Text routes List of String , delimiter: , Oral onset String BP effect 1-2 weeks; antihypertensive peak 3-6 weeks duration String 24 hours halflife String 2 hours (parent); 6-9 hours for active carboxylic acid metabolite EXP3174'"`UNIQ--ref-000000BC-QINU`"' bioavailability String ~33% (extensive first-pass via CYP2C9 and CYP3A4)'"`UNIQ--ref-000000BD-QINU`"' pregnancy String '''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, hypocalvaria, hypotension. Stop on detection'"`UNIQ--ref-000000BE-QINU`"' legal String [[USLegal:Prescription only|Rx-only]] in US
