Page values for "Omeprazole"

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"Medicines" values

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Field	Field type	Value
generic	`String`	Omeprazole
brand	`String`	Prilosec, Losec, Zegerid
structure	`File`
classes	List of `String`, delimiter: `,`	[[:Category:Proton_pump_inhibitors\|Proton pump inhibitor (PPI)]] • [[:Category:Antisecretory_agents\|Gastric acid suppressant]]
mechanism	`String`	'"`UNIQ--vote-000000D8-QINU`"' Recovery of acid output requires synthesis of new pump enzyme. CYP2C19 substrate; PGx genotype substantially affects exposure and efficacy'"`UNIQ--ref-000000D9-QINU`"'.
uses	`String`	'"`UNIQ--vote-000000DA-QINU`"', '"`UNIQ--vote-000000DB-QINU`"', '"`UNIQ--vote-000000DC-QINU`"', '"`UNIQ--vote-000000DD-QINU`"'
starting_dose	`String`	20 mg PO once daily 30-60 minutes before breakfast
preparations	`String`	10, 20, 40 mg delayed-release capsules and tablets; 2 mg/mL oral suspension; immediate-release combo with sodium bicarbonate (Zegerid)
fda_max	`String`	40 mg/d typical; up to 360 mg/d for Zollinger-Ellison
pill_id	`Text`
routes	List of `String`, delimiter: `,`	Oral • IV
onset	`String`	Symptom relief 1-4 days; full acid suppression after 3-5 days of dosing
duration	`String`	24-72 hours per dose (irreversible enzyme binding; effect outlasts plasma exposure)
halflife	`String`	0.5-1.5 hours (plasma); pharmacodynamic effect persists 24+ hours'"`UNIQ--ref-000000DE-QINU`"'
bioavailability	`String`	30-40% (oral; increases with repeated dosing as gastric pH rises)'"`UNIQ--ref-000000DF-QINU`"'
pregnancy	`String`	Widely used in pregnancy; meta-analyses do not show increased malformation risk.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed\|citation needed]]]</sup>
legal	`String`	OTC (20 mg) and [[USLegal:Prescription only\|Rx-only]] (higher doses) in US