1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Oxycodone / Acetaminophen |
| brand | String | Percocet, Endocet, Roxicet, Tylox, Primlev |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Opioid_analgesics|Opioid analgesic]] • [[:Category:Non-opioid_analgesics|Non-opioid analgesic (acetaminophen)]] • [[:Category:Schedule_II_controlled_substances|Schedule II controlled substance]] • [[:Category:Fixed-dose_combinations|Fixed-dose combination]] |
| mechanism | String | '"`UNIQ--vote-000014DD-QINU`"' The combination is the most-prescribed opioid analgesic in the US for moderate-to-severe acute pain. CPIC PGx guidance addresses CYP2D6-driven exposure variation'"`UNIQ--ref-000014DE-QINU`"'. |
| uses | String | '"`UNIQ--vote-000014DF-QINU`"', '"`UNIQ--vote-000014E0-QINU`"', '"`UNIQ--vote-000014E1-QINU`"' |
| starting_dose | String | 5 mg / 325 mg PO every 4-6 hours as needed; total acetaminophen <3 g/d |
| preparations | String | Oxycodone/acetaminophen 2.5/325, 5/325, 7.5/325, 10/325 mg tablets; 5/325 mg/5 mL solution |
| fda_max | String | Acetaminophen 4 g/d absolute (3 g/d conservative); oxycodone titrated to effect |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | 10-30 minutes |
| duration | String | 4-6 hours |
| halflife | String | Oxycodone 3-5 hours; acetaminophen 1-3 hours'"`UNIQ--ref-000014E2-QINU`"' |
| bioavailability | String | ~60-87% oxycodone (high and predictable, less CYP-genotype-dependent than codeine or hydrocodone); 85-98% acetaminophen'"`UNIQ--ref-000014E3-QINU`"' |
| pregnancy | String | Limited use in pregnancy; chronic third-trimester opioid exposure produces neonatal opioid withdrawal syndrome and respiratory depression at delivery.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Schedule II|Schedule II controlled substance]] in US. Acetaminophen content limited to ≤325 mg per dosage unit (FDA 2014) |
