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Field Field type Value generic String Progesterone (micronized) brand String Prometrium (oral), Endometrin (vaginal), Crinone (vaginal gel), Prochieve structure File classes List of String , delimiter: , [[:Category:Progestogens|Progestogen]] • [[:Category:Sex_hormones|Sex hormone]] • [[:Category:Hormone_replacement_therapy|Hormone replacement therapy]] mechanism String uses String '"`UNIQ--vote-00000722-QINU`"', '"`UNIQ--vote-00000723-QINU`"', '"`UNIQ--vote-00000724-QINU`"', '"`UNIQ--vote-00000725-QINU`"' starting_dose String HRT cyclic: 200 mg PO HS days 1-12 of each month; continuous: 100 mg PO daily; ART luteal support 100 mg vaginal TID or 90 mg gel daily preparations String Oral 100, 200 mg capsules (peanut oil; check allergy); 100 mg vaginal insert (Endometrin); 4%, 8% vaginal gel (Crinone); IM 50 mg/mL fda_max String Indication-dependent; 200-400 mg/d oral typical pill_id Text routes List of String , delimiter: , Oral • vaginal • intramuscular onset String Sedation/dizziness within hours of oral dose; endometrial effects over days duration String Oral: 8-12 hours; vaginal: 24+ hours; IM: days halflife String ~5-20 hours (oral micronized; highly variable)'"`UNIQ--ref-00000726-QINU`"' bioavailability String Oral: very low (extensive first-pass); micronization improves uptake somewhat. Vaginal: high local effect with lower systemic levels (first-uterine-pass concentration)'"`UNIQ--ref-00000727-QINU`"' pregnancy String legal String [[USLegal:Prescription only|Rx-only]] in US
