1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Psilocybin |
| brand | String | COMP360 (Compass Pathways, investigational synthesized clinical formulation) |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Psychedelics|Psychedelic]] • [[:Category:Classical Psychedelics (Serotonergic)|Serotonergic psychedelic]] • [[:Category:Tryptamines|Tryptamine]] |
| mechanism | String | Prodrug to [[Psilocin|psilocin]] (4-hydroxy-N,N-dimethyltryptamine), a partial agonist at the [[Receptor:5-HT2A|5-HT2A]] serotonin receptor; the action that defines the classical-psychedelic mechanism |
| uses | String | (investigational) '"`UNIQ--vote-000000EF-QINU`"', '"`UNIQ--vote-000000F0-QINU`"', '"`UNIQ--vote-000000F1-QINU`"', '"`UNIQ--vote-000000F2-QINU`"', '"`UNIQ--vote-000000F3-QINU`"' |
| starting_dose | String | Modern clinical-trial standard: 25 mg synthesized psilocybin, single oral dose with psychological support |
| preparations | String | Synthesized psilocybin capsules (COMP360 and other investigational formulations); dried whole [[Psilocybe|Psilocybe]] mushrooms (variable potency, no legal supply chain in most jurisdictions); psilocybin truffles (Psilocybe sclerotia, legal in the Netherlands) |
| fda_max | String | Not FDA-approved; clinical-trial protocols use up to 30 mg in adult investigational dosing |
| pill_id | Text | Investigational only; not commercially available outside clinical trials and regulated services programs |
| routes | List of String, delimiter: , | Oral |
| onset | String | 20-45 min subjective onset; psilocin formation from psilocybin requires intestinal and hepatic alkaline phosphatase |
| duration | String | 4-6 hours |
| halflife | String | Psilocin: ~2-3 h; psilocybin itself is a prodrug, dephosphorylated within minutes of absorption |
| bioavailability | String | Oral bioavailability of psilocin from administered psilocybin approximately 50% |
| pregnancy | String | Not studied in human pregnancy; no approved clinical use in any population |
| legal | String | |
