1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Quetiapine |
| brand | String | Seroquel |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Neuroleptics|Neuroleptic]] • [[:Category:Second-generation neuroleptics|Second-generation (atypical) neuroleptic]] • [[:Category:Dibenzothiazepines|Dibenzothiazepine]] • [[:Category:Serotonin-dopamine antagonists|Serotonin-dopamine antagonist]] |
| mechanism | String | Dopamine D2 and serotonin 5-HT2A receptor antagonist'"`UNIQ--ref-0000008D-QINU`"' '"`UNIQ--vote-0000008E-QINU`"' |
| uses | String | '"`UNIQ--vote-0000008F-QINU`"', '"`UNIQ--vote-00000090-QINU`"', '"`UNIQ--vote-00000091-QINU`"', '"`UNIQ--vote-00000092-QINU`"' |
| starting_dose | String | 25 mg (schizophrenia, immediate-release); 50 mg (bipolar mania, immediate-release); 50 mg (Seroquel XR, schizophrenia or bipolar) |
| preparations | String | 25 mg, 50 mg, 100 mg, 200 mg, 300 mg, 400 mg immediate-release tablets; 50 mg, 150 mg, 200 mg, 300 mg, 400 mg extended-release tablets (Seroquel XR) |
| fda_max | String | 800 mg/day |
| pill_id | Text | * '''25 mg:''' peach round film-coated tablet
* '''50 mg:''' white round film-coated tablet
* '''100 mg:''' yellow round film-coated tablet
* '''200 mg:''' white round film-coated tablet
* '''300 mg:''' white capsule-shaped film-coated tablet
* '''400 mg:''' yellow capsule-shaped film-coated tablet
* '''XR tablets:''' film-coated, varying shapes and colors by strength |
| routes | List of String, delimiter: , | Oral |
| onset | String | 30-60 min (sedation); days to weeks (neuroleptic effect) |
| duration | String | 6-8 h (immediate-release); 24 h (extended-release) |
| halflife | String | ~6 h (parent compound, immediate-release); ~9-12 h (active metabolite N-desalkylquetiapine, also called norquetiapine) |
| bioavailability | String | Tablet ~100% relative to oral solution; extensive first-pass metabolism |
| pregnancy | String | Pregnancy categories were retired by FDA in 2015. Quetiapine has reassuring active-comparator cohort data without consistent teratogenic signal; among the preferred neuroleptics when treatment is clinically necessary in pregnancy. See pregnancy_details for the full citation set. |
| legal | String | [[USLegal:Prescription only|Prescription only]]; not a controlled substance |
