Page values for "Rosuvastatin"

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"Medicines" values

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Field	Field type	Value
generic	`String`	Rosuvastatin
brand	`String`	Crestor, Ezallor
structure	`File`
classes	List of `String`, delimiter: `,`	[[:Category:Statins\|Statin]] • [[:Category:Lipid-lowering_agents\|Lipid-lowering agent]]
mechanism	`String`	'"`UNIQ--vote-000000F7-QINU`"' Minimal CYP3A4 dependence (CYP2C9 minor) reduces drug-drug interactions; transport in and out of hepatocytes is largely via OATP1B1, making SLCO1B1 PGx genotype the most clinically actionable marker for statin-associated myopathy'"`UNIQ--ref-000000F8-QINU`"'.
uses	`String`	'"`UNIQ--vote-000000F9-QINU`"', '"`UNIQ--vote-000000FA-QINU`"', '"`UNIQ--vote-000000FB-QINU`"'
starting_dose	`String`	10-20 mg PO once daily (5 mg in Asian ancestry, elderly, hypothyroidism, or strong CYP/SLCO1B1 interactions)
preparations	`String`	5, 10, 20, 40 mg tablets
fda_max	`String`	40 mg/d (rarely needed; 40 mg restricted to patients not at goal on 20 mg)
pill_id	`Text`
routes	List of `String`, delimiter: `,`	Oral
onset	`String`	LDL lowering at 1 week, max by 4 weeks
duration	`String`	24 hours
halflife	`String`	~19 hours'"`UNIQ--ref-000000FC-QINU`"'
bioavailability	`String`	~20% (oral; hydrophilic, minimal CYP metabolism, mostly excreted unchanged in bile)'"`UNIQ--ref-000000FD-QINU`"'
pregnancy	`String`	Previously Category X; FDA removed the blanket statin contraindication in pregnancy in 2021. Use individualized.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed\|citation needed]]]</sup>
legal	`String`	[[USLegal:Prescription only\|Rx-only]] in US