Page values for "Spironolactone"

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"Medicines" values

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Field	Field type	Value
generic	`String`	Spironolactone
brand	`String`	Aldactone, CaroSpir
structure	`File`
classes	List of `String`, delimiter: `,`	[[:Category:Aldosterone_antagonists\|Mineralocorticoid (aldosterone) receptor antagonist]] • [[:Category:Potassium-sparing_diuretics\|Potassium-sparing diuretic]] • [[:Category:Antiandrogens\|Antiandrogen]]
mechanism	`String`
uses	`String`	'"`UNIQ--vote-0000034F-QINU`"', '"`UNIQ--vote-00000350-QINU`"', '"`UNIQ--vote-00000351-QINU`"', '"`UNIQ--vote-00000352-QINU`"', '"`UNIQ--vote-00000353-QINU`"'
starting_dose	`String`	25 mg PO once daily for HFrEF and primary aldosteronism; up to 100 mg/d for ascites; 50-200 mg/d for hirsutism
preparations	`String`	25 mg, 50 mg, 100 mg tablets; 25 mg/5 mL oral suspension (CaroSpir)
fda_max	`String`	400 mg/d (acute primary aldosteronism diagnosis); 100-200 mg/d typical chronic
pill_id	`Text`
routes	List of `String`, delimiter: `,`	Oral
onset	`String`	Natriuresis at 2-3 days; endocrine effects (gynecomastia, antiandrogen action) over weeks
duration	`String`	Variable; biologically active metabolite carries effect beyond plasma half-life
halflife	`String`	1.4 hours (parent); 13-24 hours for active metabolite canrenone'"`UNIQ--ref-00000354-QINU`"'
bioavailability	`String`	~70% (oral; bioavailability and absorption are improved with food)'"`UNIQ--ref-00000355-QINU`"'
pregnancy	`String`	Avoid in pregnancy; antiandrogen effects can feminize a male fetus.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed\|citation needed]]]</sup>
legal	`String`	[[USLegal:Prescription only\|Rx-only]] in US