Page values for "Symbyax"

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"Medicines" values

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Field	Field type	Value
generic	`String`	Olanzapine / Fluoxetine
brand	`String`	Symbyax
structure	`File`
classes	List of `String`, delimiter: `,`	[[:Category:Neuroleptics\|Atypical neuroleptic (olanzapine)]] • [[:Category:Antidepressants\|Antidepressant (fluoxetine • SSRI)]] • [[:Category:Mood_stabilizers\|Mood stabilizer]] • [[:Category:Fixed-dose_combinations\|Fixed-dose combination]]
mechanism	`String`	'"`UNIQ--vote-00001549-QINU`"' Metabolic effects (weight gain, dyslipidemia, glucose dysregulation) dominate the long-term tolerability profile; routine metabolic monitoring is standard'"`UNIQ--ref-0000154A-QINU`"'.
uses	`String`	'"`UNIQ--vote-0000154B-QINU`"', '"`UNIQ--vote-0000154C-QINU`"'
starting_dose	`String`	6/25 mg PO once daily in the evening; titrate within range 3/25 to 18/75 mg by clinical response and tolerability
preparations	`String`	Capsules: 3/25, 6/25, 6/50, 12/25, 12/50 mg olanzapine/fluoxetine
fda_max	`String`	18 mg olanzapine / 75 mg fluoxetine per day
pill_id	`Text`
routes	List of `String`, delimiter: `,`	Oral
onset	`String`	Mood improvement at 1-3 weeks; full effect 4-6 weeks
duration	`String`	24 hours
halflife	`String`	Olanzapine ~30 hours; fluoxetine 1-4 days (norfluoxetine 7-15 days)'"`UNIQ--ref-0000154D-QINU`"'
bioavailability	`String`	Olanzapine 60% (oral); fluoxetine high (oral)'"`UNIQ--ref-0000154E-QINU`"'
pregnancy	`String`	Limited data; fluoxetine has reassuring data but olanzapine carries metabolic-syndrome and gestational diabetes signals.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed\|citation needed]]]</sup>
legal	`String`	[[USLegal:Prescription only\|Rx-only]] in US. Carries the '''antidepressant Boxed Warning''' for suicidality in children/adolescents/young adults and the atypical-neuroleptic '''Boxed Warning''' for increased mortality in elderly dementia patients'"`UNIQ--ref-0000154F-QINU`"'