1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Timolol (maleate) |
| brand | String | Timoptic (ophthalmic), Timoptic-XE (gel-forming once-daily), Istalol (once-daily 0.5%), Betimol; Blocadren (oral, discontinued in many markets); combination eye drops Combigan (with brimonidine), Cosopt (with dorzolamide) |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Beta blockers|Beta blocker (non-selective)]] • [[:Category:Antiglaucoma medicines|Antiglaucoma medicine]] • [[:Category:Antihypertensives|Antihypertensive]] • [[:Category:Migraine prophylactics|Migraine prophylactic]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-00000017-QINU`"', '"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"' |
| starting_dose | String | Ophthalmic: 1 drop 0.5% in affected eye(s) BID (or once daily for XE / Istalol). Oral hypertension: 10 mg PO BID, titrate to 60 mg/day. Migraine prophylaxis: 10 mg BID, titrate to 30 mg/day |
| preparations | String | Tablets 5, 10, 20 mg; ophthalmic solution 0.25%, 0.5%; ophthalmic gel-forming solution 0.25%, 0.5% (Timoptic-XE) |
| fda_max | String | 60 mg/day (oral, hypertension); 0.5% BID (ophthalmic) |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral • ophthalmic |
| onset | String | BP effect within hours (oral); IOP reduction within 30 minutes, full effect 1-2 weeks (ophthalmic) |
| duration | String | 12 hours (oral BID); 24 hours (Timoptic-XE) |
| halflife | String | ~4 hours (oral)'"`UNIQ--ref-0000001B-QINU`"' |
| bioavailability | String | ~50% (oral); systemic absorption from ophthalmic application is clinically meaningful via nasolacrimal drainage'"`UNIQ--ref-0000001C-QINU`"' |
| pregnancy | String | Limited human data; β-blocker class effects include fetal growth restriction and neonatal bradycardia/hypoglycemia.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US |
