1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Topiramate |
| brand | String | Topamax (IR), Trokendi XR, Qudexy XR, Eprontia (oral solution); component of Qsymia (with phentermine) |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Anticonvulsants|Anticonvulsant]] • [[:Category:Migraine prophylactics|Migraine prophylactic]] • [[:Category:Weight loss medicines|Weight loss medicine]] • [[:Category:Sodium channel blockers|Sodium channel blocker]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"', '"`UNIQ--vote-00000026-QINU`"', '"`UNIQ--vote-00000027-QINU`"' |
| starting_dose | String | Migraine: 25 mg PO at bedtime, titrate by 25 mg weekly to target 100 mg/day divided BID. Seizures: 25-50 mg/day, titrate weekly to 200-400 mg/day divided BID |
| preparations | String | IR tablets 25, 50, 100, 200 mg; sprinkle capsules 15, 25 mg; Trokendi XR capsules 25, 50, 100, 200 mg; Qudexy XR capsules; Eprontia oral solution 25 mg/mL |
| fda_max | String | 1600 mg/day (theoretical seizure dosing); practical use 400 mg/day for seizures, 100-200 mg/day for migraine prophylaxis |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | Anticonvulsant effect within days at therapeutic level; migraine prophylaxis effect emerges over 2-3 months |
| duration | String | 12-24 hours (IR BID); 24 hours (ER once-daily) |
| halflife | String | ~21 hours'"`UNIQ--ref-00000028-QINU`"' |
| bioavailability | String | ~80% (oral)'"`UNIQ--ref-00000029-QINU`"' |
| pregnancy | String | '''Substantial teratogenic risk''' including cleft lip/palate, hypospadias, and growth restriction (pregnancy registry data clear); effective contraception and pre-pregnancy counseling are required in reproductive-age patients'"`UNIQ--ref-0000002A-QINU`"' |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US. Not a controlled substance'"`UNIQ--ref-0000002B-QINU`"' |
