Page values for "Azelastine"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Azelastine |
| brand | String | Astelin, Astepro (intranasal); Optivar (ophthalmic); with fluticasone as Dymista |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:H1_receptor_antagonists|Histamine H1 receptor antagonist]] • [[:Category:Mast_cell_stabilizers|Mast cell stabilizer]] • [[:Category:Intranasal_antihistamines|Intranasal antihistamine]] |
| mechanism | String | '"`UNIQ--vote-000013B1-QINU`"' Topical application minimizes systemic antihistaminic burden; the characteristic bitter taste with nasal use (drainage to oropharynx) is the main tolerability issue'"`UNIQ--ref-000013B2-QINU`"'. |
| uses | String | '"`UNIQ--vote-000013B3-QINU`"', '"`UNIQ--vote-000013B4-QINU`"', '"`UNIQ--vote-000013B5-QINU`"' |
| starting_dose | String | Intranasal 0.1% or 0.15%: 1-2 sprays/nostril BID; ophthalmic 0.05%: 1 drop in each eye BID |
| preparations | String | 0.1%, 0.15% intranasal spray; 0.05% ophthalmic solution; combination Dymista (azelastine 0.137 mg + fluticasone 50 mcg/spray) |
| fda_max | String | 2 sprays/nostril BID |
| pill_id | Text | |
| routes | List of String, delimiter: , | Intranasal • topical ophthalmic |
| onset | String | 15 minutes |
| duration | String | 12 hours |
| halflife | String | ~22 hours; longer 54 hours (desmethylazelastine, active metabolite)'"`UNIQ--ref-000013B6-QINU`"' |
| bioavailability | String | Intranasal ~40% systemic; ophthalmic minimal'"`UNIQ--ref-000013B7-QINU`"' |
| pregnancy | String | Limited data; second-line to intranasal corticosteroids or PO loratadine/cetirizine.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | OTC (Astepro 0.15%) and [[USLegal:Prescription only|Rx-only]] (other intranasal, ophthalmic, Dymista) in US |