Page values for "Buspirone"
From Pharmacopedia
More actions
"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Buspirone |
| brand | String | Buspar (US brand discontinued; generic widely available) |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Anxiolytics|Anxiolytic]] • [[:Category:Azapirones|Azapirone]] • [[:Category:Serotonin 5-HT1A partial agonists|Serotonin 5-HT1A partial agonist]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"', '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"' |
| starting_dose | String | 5 mg PO TID or 7.5 mg PO BID; titrate by 5 mg every 2-3 days to clinical effect, commonly 30-60 mg/day divided BID-TID |
| preparations | String | Tablets 5, 7.5, 10, 15, 30 mg (the 15 and 30 mg tablets are scored for halving and quartering) |
| fda_max | String | 60 mg/day |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | '''Anxiolytic effect emerges over 2-4 weeks'''; buspirone does NOT work for acute anxiety, which is the central teaching point and the most common cause of treatment failure |
| duration | String | ~8 hours (TID dosing) |
| halflife | String | Buspirone 2-3 hours; 1-PP active metabolite 4-6 hours'"`UNIQ--ref-0000001D-QINU`"' |
| bioavailability | String | ~4% (extensive first-pass metabolism)'"`UNIQ--ref-0000001E-QINU`"' |
| pregnancy | String | Limited human data; older agent with substantial use experience and no clear teratogenic signal.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US. Not a controlled substance, which is a meaningful clinical advantage over benzodiazepine alternatives for chronic anxiety'"`UNIQ--ref-0000001F-QINU`"' |