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Page values for "Cetirizine"

From Pharmacopedia
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"Medicines" values

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FieldField typeValue
genericStringCetirizine
brandStringZyrtec, Zyrtec-D
structureFile
classesList of String, delimiter: ,[[:Category:H1_receptor_antagonists|Histamine H1 receptor antagonist (second-generation)]] [[:Category:Antihistamines|Antihistamine]]
mechanismString'"`UNIQ--vote-00000391-QINU`"' Minimal CYP metabolism; mostly renally cleared unchanged. Cetirizine is the active racemate; levocetirizine is the active R-enantiomer marketed separately'"`UNIQ--ref-00000392-QINU`"'.
usesString'"`UNIQ--vote-00000393-QINU`"', '"`UNIQ--vote-00000394-QINU`"', '"`UNIQ--vote-00000395-QINU`"'
starting_doseString10 mg PO once daily (5 mg in older adults or if sedation occurs)
preparationsString5 mg, 10 mg tablets; 5 mg, 10 mg chewables; 1 mg/mL oral syrup; OTC
fda_maxString10 mg/d (adults)
pill_idText
routesList of String, delimiter: ,Oral
onsetString30-60 minutes
durationString24 hours
halflifeString8-10 hours (longer in elderly and renal impairment)'"`UNIQ--ref-00000396-QINU`"'
bioavailabilityStringHigh (oral); not significantly affected by food'"`UNIQ--ref-00000397-QINU`"'
pregnancyStringGenerally considered safe; widely used. Levocetirizine (the R-enantiomer) is an alternative with similar safety.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup>
legalStringOTC in US