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Page values for "Cholecalciferol"

From Pharmacopedia
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"Medicines" values

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FieldField typeValue
genericStringCholecalciferol (vitamin D3)
brandStringMany OTC; Rx 50,000 IU also available
structureFile
classesList of String, delimiter: ,[[:Category:Vitamin_D_analogs|Vitamin D analog]] [[:Category:Fat-soluble_vitamins|Fat-soluble vitamin]]
mechanismString'"`UNIQ--vote-0000042C-QINU`"' D3 is more potent than D2 at raising and sustaining serum 25(OH)D per dose, and is the more common OTC formulation; D2 remains the dominant Rx 50,000 IU formulation in the US for historical reasons.
usesString'"`UNIQ--vote-0000042D-QINU`"', '"`UNIQ--vote-0000042E-QINU`"', '"`UNIQ--vote-0000042F-QINU`"', '"`UNIQ--vote-00000430-QINU`"'
starting_doseStringMaintenance 800-2,000 IU PO daily; deficiency replacement 50,000 IU PO weekly for 8-12 weeks then maintenance, or equivalent daily dosing 5,000-10,000 IU/d
preparationsStringOTC 400, 1,000, 2,000, 5,000 IU softgels and tablets; Rx 50,000 IU capsules; liquid drops 400-2,000 IU/drop
fda_maxStringNo strict; Institute of Medicine UL 4,000 IU/d in adults for chronic use
pill_idText
routesList of String, delimiter: ,Oral IM (rare for severe malabsorption)
onsetStringWeeks to raise 25(OH)D into reference range
durationStringLong; fat-soluble storage in adipose
halflifeString~24 hours (parent); ~15 days (25(OH)D); tissue stores months
bioavailabilityString~75% (oral; absorption improved with fat-containing meal)
pregnancyStringSafe at replacement doses; deficiency is itself a risk in pregnancy and lactation.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup>
legalStringOTC (most) and [[USLegal:Prescription only|Rx-only]] (50,000 IU) in US