Page values for "Citalopram"

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"Medicines" values

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Field	Field type	Value
generic	`String`	Citalopram
brand	`String`	Celexa
structure	`File`
classes	List of `String`, delimiter: `,`	[[:Category:SSRIs\|Selective serotonin reuptake inhibitor (SSRI)]] • [[:Category:Antidepressants\|Antidepressant]]
mechanism	`String`	'"`UNIQ--vote-0000001D-QINU`"' CYP2C19 + CYP3A4 metabolism, with CPIC PGx guidance: poor CYP2C19 metabolizers have ~3-fold higher exposure and benefit from a lower starting dose; ultrarapid metabolizers may have inadequate response'"`UNIQ--ref-0000001E-QINU`"'.
uses	`String`	'"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"'
starting_dose	`String`	20 mg PO once daily; titrate to 40 mg/day after 1 week if tolerated. Elderly (>60) and hepatic impairment: 20 mg/day ceiling
preparations	`String`	Tablets 10, 20, 40 mg; oral solution 10 mg/5 mL
fda_max	`String`	'''20 mg/day in adults >60 years''' per FDA's 2011-2012 QT-prolongation warning; 40 mg/day in adults ≤60
pill_id	`Text`
routes	List of `String`, delimiter: `,`	Oral
onset	`String`	Antidepressant effect over 1-2 weeks; full clinical effect 4-6 weeks
duration	`String`	24 hours (once-daily dosing)
halflife	`String`	~35 hours'"`UNIQ--ref-00000026-QINU`"'
bioavailability	`String`	~80% (oral)'"`UNIQ--ref-00000027-QINU`"'
pregnancy	`String`	Observational signal for persistent pulmonary hypertension of the newborn (small absolute risk) and neonatal adaptation syndrome with third-trimester exposure.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed\|citation needed]]]</sup>
legal	`String`	[[USLegal:Prescription only\|Rx-only]] in US. Carries the antidepressant '''Boxed Warning''' for suicidality in children, adolescents, and young adults'"`UNIQ--ref-00000028-QINU`"'