Page values for "Diltiazem"

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"Medicines" values

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Field	Field type	Value
generic	`String`	Diltiazem
brand	`String`	Cardizem, Tiazac, Cartia XT, Dilacor XR, Taztia XT, Matzim LA
structure	`File`
classes	List of `String`, delimiter: `,`	[[:Category:Calcium_channel_blockers\|Calcium channel blocker (non-dihydropyridine)]] • [[:Category:Antianginals\|Antianginal]] • [[:Category:Antiarrhythmics\|Antiarrhythmic (class IV)]] • [[:Category:Antihypertensives\|Antihypertensive]]
mechanism	`String`	'"`UNIQ--vote-0000063C-QINU`"' Avoid in HFrEF (negative inotropy). CYP3A4 substrate AND moderate inhibitor — interacts substantially with statins (especially simvastatin), tacrolimus, cyclosporine, and many other CYP3A4 substrates'"`UNIQ--ref-0000063D-QINU`"'.
uses	`String`	'"`UNIQ--vote-0000063E-QINU`"', '"`UNIQ--vote-0000063F-QINU`"', '"`UNIQ--vote-00000640-QINU`"', '"`UNIQ--vote-00000641-QINU`"'
starting_dose	`String`	ER 180-240 mg PO once daily; IR 30 mg PO QID; IV 0.25 mg/kg over 2 min for acute rate control, then 5-15 mg/h infusion
preparations	`String`	IR 30, 60, 90, 120 mg tablets; multiple ER capsules and tablets 60-420 mg; IV 5 mg/mL
fda_max	`String`	~480 mg/d (oral); IV per protocol
pill_id	`Text`
routes	List of `String`, delimiter: `,`	Oral (IR • multiple ER formulations) • IV
onset	`String`	IV: 3-7 minutes (rate control); PO IR: 30-60 minutes; ER: hours
duration	`String`	IR: 4-8 hours; ER: 24 hours
halflife	`String`	3-4.5 hours (IR); 5-7 hours (ER; effective duration 24 hours via formulation)'"`UNIQ--ref-00000642-QINU`"'
bioavailability	`String`	~40% (oral; extensive first-pass via CYP3A4)'"`UNIQ--ref-00000643-QINU`"'
pregnancy	`String`	Limited data; labetalol/nifedipine generally preferred. Crosses placenta.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed\|citation needed]]]</sup>
legal	`String`	[[USLegal:Prescription only\|Rx-only]] in US