Page values for "Fexofenadine"
From Pharmacopedia
More actions
"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Fexofenadine |
| brand | String | Allegra, Allegra Allergy 24 Hour, Mucinex Allergy (combo) — all now OTC in US |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:H1_receptor_antagonists|Histamine H1 receptor antagonist (second-generation)]] • [[:Category:Antihistamines|Antihistamine]] |
| mechanism | String | '"`UNIQ--vote-00000CC9-QINU`"' Mostly excreted unchanged in feces and urine; P-glycoprotein substrate (the basis of the fruit-juice interaction). |
| uses | String | '"`UNIQ--vote-00000CCA-QINU`"', '"`UNIQ--vote-00000CCB-QINU`"' |
| starting_dose | String | 60 mg PO BID or 180 mg PO once daily |
| preparations | String | 30, 60, 180 mg tablets; 30 mg ODT; 6 mg/mL oral suspension; all OTC |
| fda_max | String | 180 mg/d (adults) |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | 1-2 hours |
| duration | String | 12-24 hours |
| halflife | String | ~14 hours'"`UNIQ--ref-00000CCC-QINU`"' |
| bioavailability | String | ~33% (oral; fruit juices including grapefruit, orange, and apple reduce absorption substantially via OATP1A2 inhibition — distinctive interaction not seen with most other H1s)'"`UNIQ--ref-00000CCD-QINU`"' |
| pregnancy | String | Generally considered safe; loratadine and cetirizine have more pregnancy data and are typically preferred.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | OTC in US |