Page values for "Flecainide"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Flecainide |
| brand | String | Tambocor (US brand discontinued) |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Antiarrhythmics|Antiarrhythmic (Vaughan-Williams class IC)]] |
| mechanism | String | '"`UNIQ--vote-0000113A-QINU`"' Concomitant β-blocker or CCB is required when used for AF to prevent 1:1 atrial flutter conduction (flecainide can slow atrial rate to a level where AV conduction allows dangerous ventricular rates). CYP2D6 substrate'"`UNIQ--ref-0000113B-QINU`"'. |
| uses | String | '"`UNIQ--vote-0000113C-QINU`"', '"`UNIQ--vote-0000113D-QINU`"', '"`UNIQ--vote-0000113E-QINU`"' |
| starting_dose | String | 50 mg PO BID; titrate to 100-200 mg BID; pill-in-pocket 200-300 mg PO single dose for AF conversion |
| preparations | String | 50, 100, 150 mg tablets |
| fda_max | String | 400 mg/d |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | AF conversion within hours of single PO dose |
| duration | String | 12 hours |
| halflife | String | ~14 hours (adults); longer in elderly and renal impairment'"`UNIQ--ref-0000113F-QINU`"' |
| bioavailability | String | ~90% (oral)'"`UNIQ--ref-00001140-QINU`"' |
| pregnancy | String | Use in fetal SVT (transplacental antiarrhythmic therapy) is established; otherwise weigh against alternatives.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US. '''Contraindicated in structural heart disease''' — CAST trial (1989) showed increased mortality from class IC agents in patients with prior MI; modern use is limited to structurally normal hearts'"`UNIQ--ref-00001141-QINU`"' |