Page values for "Hydralazine"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Hydralazine |
| brand | String | Apresoline (historical); mostly generic; combination with isosorbide dinitrate marketed as BiDil for self-identified Black patients with HFrEF |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Direct_vasodilators|Direct arteriolar vasodilator]] • [[:Category:Antihypertensives|Antihypertensive]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-00000683-QINU`"', '"`UNIQ--vote-00000684-QINU`"', '"`UNIQ--vote-00000685-QINU`"', '"`UNIQ--vote-00000686-QINU`"' |
| starting_dose | String | PO 10 mg QID; IV 5-10 mg every 20-30 minutes for hypertensive emergency |
| preparations | String | 10, 25, 50, 100 mg tablets; 20 mg/mL IV |
| fda_max | String | 300 mg/d typical practical limit (toxicity rises sharply above) |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral • IV • IM |
| onset | String | IV: 5-20 minutes; PO: 30-60 minutes |
| duration | String | IV: 1-4 hours; PO: 3-8 hours |
| halflife | String | 3-7 hours (slow acetylators) vs 1-3 hours (rapid acetylators) via NAT2 polymorphism'"`UNIQ--ref-00000687-QINU`"' |
| bioavailability | String | ~25-50% (oral; substantial first-pass via NAT2 acetylation, phenotype-dependent)'"`UNIQ--ref-00000688-QINU`"' |
| pregnancy | String | One of the historically preferred IV agents for severe hypertension in pregnancy alongside labetalol and nifedipine.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US |