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Page values for "Lidocaine"

From Pharmacopedia
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"Medicines" values

1 row is stored for this page
FieldField typeValue
genericStringLidocaine (hydrochloride)
brandStringXylocaine (injectable, oral solution, topical), Lidoderm (patch), ZTLido (patch), Glydo (jelly), EMLA (with prilocaine, topical)
structureFile
classesList of String, delimiter: ,[[:Category:Local anesthetics|Local anesthetic (amide class)]] [[:Category:Anesthetics|Anesthetic]] [[:Category:Antiarrhythmics|Antiarrhythmic (Vaughan Williams Class IB)]]
mechanismString
usesString'"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"'
starting_doseStringInfiltration: 1-2% solution; '''4.5 mg/kg ceiling without epinephrine, 7 mg/kg with epinephrine'''. IV antiarrhythmic: 1-1.5 mg/kg bolus then infusion 1-4 mg/minute. Lidoderm patch: up to 3 patches per 12 hours
preparationsStringInjection 0.5-4% solutions (with and without epinephrine); topical cream 4-5%; transdermal patch 5% (Lidoderm), 1.8% (ZTLido); oral 2% viscous solution; jelly 2%; ophthalmic
fda_maxString'''4.5 mg/kg (without epinephrine), 7 mg/kg (with epinephrine)''' for infiltration; serum level monitoring required for prolonged IV antiarrhythmic use
pill_idText
routesList of String, delimiter: ,Topical infiltration intravenous regional anesthesia (spinal epidural nerve block) oral mucosal
onsetString<1 minute (IV); 1-2 minutes (infiltration); 30+ minutes (patch on adult skin, faster on thinner pediatric skin)
durationString30-90 minutes (infiltration without epinephrine); 90-200 minutes (with epinephrine); 12 hours (patch)
halflifeString1.5-2 hours'"`UNIQ--ref-00000020-QINU`"'
bioavailabilityString~35% (oral, extensive first-pass; not used orally for systemic effect); ~100% (IV)'"`UNIQ--ref-00000021-QINU`"'
pregnancyStringExtensive use experience in obstetric anesthesia; broadly considered safe'"`UNIQ--ref-00000022-QINU`"'
legalString[[USLegal:Prescription only|Rx-only]] for most formulations; some low-concentration topical formulations are [[USLegal:Over-the-counter|OTC]] (4% cream)